Nurse Teaching Topic: Contraindications for Taking Alogliptin

 Patient/caregiver was educated on contraindications for taking Alogliptin as follows:
  1. Alogliptin for the significant part is excreted unchanged by the kidneys with very small portion being metabolized in the liver. Individuals with liver and renal dysfunction, cannot metabolize and excrete Alogliptin normally. In such patients with compromised liver and renal functions, Alogliptin can stay active in circulation for longer time and can result in serious hypoglycemic episodes. So, Alogliptin is contraindicated in such individuals.
  2. Acute pancreatitis is a rare, but serious side effect of using Alogliptin. Patients present with a severe upper abdominal pain, radiating to the back, along with nausea and vomiting. Alogliptin is contraindicated in individuals with history of acute pancreatitis.
  3. Patients taking Alogliptin rarely can present with an acute gross reduction in urine volume or with absolutely no urine formation. So, Alogliptin is contraindicated in individuals with history of compromised renal function.