Sarafem use, especially along with a few other antidepressants, such as, imipramine, citalopram, and sertraline, can significantly increase the serotonin levels in the body and lead to development of serotonin syndrome. Caution must be exercised even when discontinuing on any of the above mentioned antidepressant medications with potential to increase serotonin levels and starting on Sarafem, by observing a window period of atleast 2 weeks, before the transition to Sarafem is made. Using Sarafem with [...]

Patient/caregiver was educated on contraindications for using Sarafem as follows: Sarafem can interact with a number of other medications and can precipitate serious reactions. If you are being newly started on Sarafem, discuss with your physician regarding all other medications you are currently taking and their safety with Sarafem. Also, if you have been taking Sarafem for long, discuss with your physician regarding your history of Sarafem intake, when you are being started on any [...]

Patient/caregiver was educated on the side effects of using Sarafem as follows: Other constitutional side-effects Individuals taking Sarafem can also present with sexual dysfunctions, such as, compromised interest in sex, difficulty attaining and maintaining erection, and/or difficulty having an orgasm. Metabolic side-effects Sarafem can inhibit enzyme systems in the liver that are needed for the metabolism of dietary nutrients and various other medications. Inhibition of these enzymes systems can result in slowing of overall metabolism. [...]

Patient/caregiver was educated on the side effects of using Sarafem as follows: Gastrointestinal side-effects                                                                                                             Sarafem use can result in common general constitutional symptoms such as, nausea and vomiting, especially when taken on empty stomach. Taking dose of Sarafem with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication. Sarafem can also induce diarrhea. Proper hydration measures and compliance with daily fluid intake and [...]

Patient/caregiver was educated on the side effects of using Sarafem as follows: Central nervous system side-effects Sarafem can induce some dizziness and make one drowsy. Starting the medication at a low dose, watching for the response, and gradually changing the dose, to help optimum control of your symptoms, can contribute to controlling/reducing the risk for drowsiness and dizziness due to the medication. If the dizziness becomes bothersome, report it to your physician and other health [...]