Contraindications for Topiramate Use-2
Patient/caregiver was educated on contraindications for using topiramate as follows: Diabetic patients, especially individuals with poorly controlled grossly elevated blood sugars, can develop ketosis, secondary to increased fat metabolism. In these individuals, secondary to lack of insulin, glucose could not be transported into the cells and so, is not available for metabolism and cellular needs. The cells depend on fat, as an alternate fuel, to meet the metabolic demand. Consequently, the cells produce ketone bodies, [...]