Patient/caregiver was educated on contraindications for using Endep as follows: Endep can interact with many antibacterial and antifungal antibiotics, antiarrhythmic medications, antidepressants, and antipsychotic medications, resulting in development or aggravation of underlying cardiac arrhythmias, leading to debility and sudden cardiac death. Avoid taking Endep along with medications belonging to the above-mentioned groups, to prevent any dangerous arrhythmias from developing. Endep is mainly metabolized in the liver. If liver function is deficient, the metabolism of Endep [...]

Patient/caregiver was educated on contraindications for using Endep as follows: Endep use, especially along with a few other antidepressants, such as, citalopram, fluoxetine, and sertraline, can significantly increase the serotonin levels in the body and lead to development of serotonin syndrome. Caution must be exercised even when discontinuing on any of the above mentioned antidepressant medications with potential to increase serotonin levels and starting on Endep, by observing a window period of atleast 2 weeks, [...]

Patient/caregiver was educated on contraindications for using Endep as follows: Endep can interact with a number of other medications and can precipitate serious reactions. If you are being newly started on Endep, discuss with your physician regarding all other medications you are currently taking and their safety with Endep. Also, if you have been taking Endep for long, discuss with your physician regarding your history of Endep intake, when you are being started on any [...]

Patient/caregiver was educated on the side-effects of using Endep as follows: Musculoskeletal side-effects Endep intake carries the risk of lowering the threshold for seizures, thereby, resulting in seizure activity, especially in individuals with history of the same. Endep intake can also induce a life-threatening reaction called Neuroleptic malignant syndrome. Individuals taking Endep can present with high fever, episodes of confusion, muscle rigidity, elevated blood pressure, and rapid heart rate. Severe cases can present with muscle breakdown, [...]

Patient/caregiver was educated on the side-effects of using Endep as follows: Gastrointestinal side-effects                                                                  Endep use can result in common general constitutional symptoms such as, nausea and vomiting. Taking dose of Endep with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication. Endep can also induce extreme dry mouth and constipation. Sucking on a sugar free hard candy can help with symptomatic relief of [...]