Patient/caregiver was instructed upon therapeutic uses of Endep as follows: Bed-wetting in children Action of the neurochemical acetylcholine on the smooth muscle of bladder results in contraction of bladder, bladder emptying, and urination. Endep reportedly inhibits the action of acetylcholine on the bladder and thus, inhibits bladder emptying. This action of Endep helps with preventing/reducing episodes of nocturnal urination and bed-wetting in children. Bipolar disorder Endep can be used along with other antipsychotics for management [...]

Patient/caregiver was instructed upon therapeutic uses of Endep as follows: Major depression Endep, by inhibiting the reuptake of serotonin and noradrenaline, enhances the actions of these chemicals in the nerve cells. This helps with improved communication, appropriate desired nerve stimulation, thus contributing to controlling symptoms of depression, such as, disturbed sleep, diminishing appetite, compromised energy levels, exhaustion, and lack of interest in activities of daily living. Bulimia nervosa Binge eating and purging, characteristically seen in [...]

Patient/caregiver was instructed upon Endep and mechanism of action as follows: Neurotransmitters are chemicals that are manufactured in the brain and released by nerve endings, at the synapse, which is a junction between two nerves. This released neurotransmitter in the synapse communicates the impulse to the nerves around. This action of the neurotransmitter is terminated by reuptake of the chemical, back into the nerve ending. This reuptake of the chemical reduces the communication with the [...]