Patient/caregiver was instructed upon therapeutic uses of Adrenaline as follows:

Adrenaline acts by interacting with alpha and beta receptors located in different body tissues, in various clinical conditions discussed below. The actions of Adrenaline depend and vary widely based on the dose administered and the receptors activated.

Exacerbation of asthma

• Beta-2 receptors are chiefly located in the smooth muscle of the respiratory tract and blood vessels.
• Stimulation of these receptors by Adrenaline can result in relaxation of the bronchial and vascular smooth muscle.
• Adrenaline administered in small doses, by bringing relaxation of bronchial smooth muscle, can help better breathing patterns, promote better airflow, and reduce wheezing and SOB in individuals with acute exacerbation of asthma.

Allergies and anaphylaxis

• Also, Adrenaline, by stimulating alpha-1 receptors, reduces the permeability of blood vessels and brings on narrowing of blood vessels.
• Reduced blood vessel permeability can help with reducing the swelling of tongue and throat in individuals presenting with an allergic response or anaphylactic shock, secondary to insect bites, food, medications, and latex.
• Also, vasoconstriction in these individuals can lead to increase in blood pressure, thus reversing the hypotension caused by allergic response and anaphylaxis.
• Stimulation of Beta-2 receptors in these individuals with Adrenaline use can lead to relaxation of bronchial smooth muscle, improved breathing patterns, and better airflow.
• This helps reduce wheezing and SOB, characteristic of allergic and anaphylactic responses.