Patient/caregiver was educated on precautions to be exercised while taking tizanidine as follows: Tizanidine is mainly metabolized inside the body by the liver and is excreted out of the body in the urine by the kidneys. If liver is deficient, metabolism of the drug could be compromised, which can result in higher concentrations of the drug in the body for longer periods of time. If kidney function is deficient, elimination of the drug could be [...]

Patient/caregiver was educated on precautions to be exercised while taking tizanidine as follows: Tizanidine only helps with relieving muscle spasms, by inhibiting the conduction of nerve impulses from the spinal cord to the skeletal muscles. Tizanidine only temporarily relieves the spasms but does not fix the actual condition causing the muscle spasms and so, is not a permanent cure. Continue taking tizanidine as ordered, even if you experience relief from muscle pain and spasms, until [...]

Patient/caregiver was educated on precautions to be exercised while taking tizanidine as follows: Tizanidine, especially when taken in high doses, carries the risk of depressing the cardiovascular center in the brain, which regulates the heart rate and blood pressure. Consequently, intake of tizanidine can result in low heart rate and blood pressure. Hypotension and bradycardia, secondary to tizanidine intake, can contribute to the confusion and dizziness, thus significantly increasing the risk for fall and accidents. [...]

Patient/caregiver was educated on precautions to be exercised while taking tizanidine as follows: Tizanidine can also induce extreme dry mouth and constipation. Sucking on a sugar free hard candy can help with symptomatic relief of dry mouth. Proper hydration measures and compliance with daily fluid intake recommendations can help with relief from constipation. If you experience any further bothersome constipation, report it to your physician for a recommendation on laxative/stool softener use. Observing compliance with [...]

Patient/caregiver was educated on precautions to be exercised while taking tizanidine as follows: Follow closely on the expiration date of the medication. If using a pillbox, check the expiration date on the medication container every time you fill the pillbox. If you are taking this medication for longer periods of time, set enough reminders to help yourself pick the refill before you run out on the medication. Also, you can avoid the unpleasant withdrawal response [...]