Patient/caregiver was educated on precautions to be exercised while taking Tamoxifen as follows: While using tamoxifen for control of breast cancer, observe compliance with instructions regarding self-examining the breast. Palpate the breast at least once a month, using both the palm of the hand and the finger tips, starting at the nipple and moving in larger circles to the outer edge of the breast. This helps identify any increase in the size of the tumor [...]

Patient/caregiver was educated on precautions to be exercised while taking Tamoxifen as follows: Tamoxifen is mainly metabolized in the liver. If liver function is deficient, the metabolism of tamoxifen can be compromised. This can lead to increased blood levels of the medication and metabolites for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. Also, tamoxifen intake can result in hepatitis, fatty changes in the liver, and compromised liver function. Individuals [...]

Patient/caregiver was educated on precautions to be exercised while taking Tamoxifen as follows: Tamoxifen use carries the risk for clot formation, resulting in deep venous thrombosis (DVT) and pulmonary embolism. Individuals can present with symptoms such as, pain and swelling of extremities - especially swelling of the lower extremities with pain in the calf muscle, episode of sudden cough and shortness of breath, episode of chest pain, and any sudden vision changes. Report to your [...]

Patient/caregiver was educated on precautions to be exercised while taking Tamoxifen as follows: Warfarin and tamoxifen are metabolized by the same enzyme systems in the liver and so, compete mutually for the enzymes. Taken concurrently, tamoxifen can take over all the enzyme for metabolism, thus slowing down metabolism of warfarin. Warfarin could remain active in the blood for unduly long time, thus increasing risk for prolonged anticoagulation. Individuals taking these two drugs together can present [...]

Patient/caregiver was educated on precautions to be exercised while taking Tamoxifen as follows: In sexually active women of childbearing age group, therapy with tamoxifen should be initiated during menstruation. If tamoxifen therapy were to continue, sexually active women should avoid getting pregnant, atleast for two months, after the therapy with tamoxifen ends and must employ effective contraceptive measures in order to avoid getting pregnant. Tamoxifen compromises the therapeutic effects of hormonal contraceptives, such as, birth [...]