How to Take Spironolactone

Patient was educated on how to take Spironolactone as follows: Take the medication at the same time every day, to avoid forgetting the medication. Take Spironolactone during the day time hours and avoid having it during the night. As this medication increases the frequency of urination, taking this during the late evening hours can disturb the sleep. Maintain strict compliance with intake of Spironolactone as ordered, with regards to dosage and frequency, to derive the [...]

Spironolactone and Mechanism of Action

Patient was educated on Spironolactone and its mechanism of action as follows: Spironolactone is a potassium sparing diuretic that acts on the distal convoluted tubule and collecting duct, both parts of the renal tubule, involved in the reabsorption of water and solutes from the urine. Action of aldosterone on the collecting duct results in absorption of sodium and water from the collecting duct of the kidney and excretion of potassium in the urine. Spironolactone use [...]