Patient/caregiver was instructed upon therapeutic uses of Ryanodex as follows: Brain and spinal cord injury Individuals with brain and spinal cord damage from mechanical injuries, work injuries, and automobile accidents, present with intense muscle tightness and spasticity. Muscle spasticity can lead to contractures, rigidity, stiffness, and limited range of motion contributing to severe limitation of performance on activities of daily living, significant pain, and discomfort. Ryanodex intake in these individuals can help relieve the spasticity [...]

Patient/caregiver was instructed upon mechanism of action of Ryanodex as follows: Nerve impulses travel from the brain and spinal cord (central nervous system) along the nerves to the muscles. Upon conduction of the impulse to the muscles, calcium ion is released from the storage sites inside the muscle. This release of calcium helps the contractile units of muscle fibers to slide against one another, resulting in muscle contraction. Thus, calcium plays a significant role in [...]