Patient/caregiver was instructed upon indications for prednisone use as follows: Inflammatory states: Release of prostaglandins and leukotrienes, which are the major inflammatory mediators, contribute to pain, swelling, and respiratory smooth muscle contraction during flare-up of inflammatory states, such as, exacerbation of arthritis, ankylosing spondylitis, and asthma. Prednisone, by inhibiting the release of these mediators help with relief of these symptoms of acute inflammation, thus controlling pain and swelling in various tissues and relieving shortness of [...]

Patient/caregiver was instructed upon therapeutic uses of and mechanism of action of prednisone as follows Prednisone is a steroid medication belonging to the class of corticosteroids. Therapeutic uses of prednisone mainly involve activation of allergies, exacerbation of immune responses, and inflammatory states. Prednisone helps prevent the release of immune mediators, such as, interleukins and tumor necrosis factor, which play a key role in allergy and immune response. This action of prednisone contributes to suppressing overactive [...]