Patient/caregiver was educated on contraindications for using Metaxall as follows: Metaxall use, especially along with antidepressants, such as, citalopram, fluoxetine, sertraline, and many others can significantly increase the serotonin levels in the body. Very excessive concentrations of serotonin in the brain can lead to serotonin syndrome. Individuals with serotonin syndrome can present with mania, excitement, hallucinations, agitation, insomnia, pounding heartbeat, very rapid heart rate, overactive reflexes, and diarrhea. Metaxall use, especially in individuals with seizure [...]

Patient/caregiver was educated on contraindications for using Metaxall as follows: Metaxall is extensively metabolized in the liver and the inactive metabolites are mainly excreted in the urine. If liver function is deficient, the metabolism of metaxall can be compromised. This can lead to increased blood levels of the medication for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. So, in individuals with history of compromised liver function, metaxall must be [...]

Patient/caregiver was educated on contraindications for using Metaxall as follows: Metaxall, especially when taken in high doses, can lead to depression of respiratory center in the brain, exacerbation of SOB, and difficulty breathing. Low oxygen levels in the body with elevated carbon-di-oxide levels can contribute to altered levels of consciousness, sedation, slow & shallow breathing, severely compromised endurance and exercise tolerance, extreme fatigue, and development of seizures. Severe cases might also lead to emergency situations, [...]

Patient/caregiver was educated on the side-effects of using Metaxall as follows: Hematologic side-effects Metaxall intake can sometimes result in breakdown of red blood cells in the circulation. Patients can present with symptoms of anemia, such as pale skin and mucous membranes, exacerbation of shortness of breath, dizziness due to reduced oxygen supply to the brain, and weakness. Damaged red blood cells also contribute to elevated bilirubin pigment in the blood, thus contributing to findings of [...]

Patient/caregiver was educated on the side-effects of using Metaxall as follows: General allergic reactions                                  Metaxall use can result in general allergic reactions, such as, skin rashes, hives, and itching. Some patients can present with symptoms of severe allergic and anaphylactic response with metaxall, such as, difficulty breathing, swelling of face, lips, throat, and tongue, with consequent difficulty breathing. Seek emergency medical help for such findings, especially with difficulty breathing, for any appropriate measures to be [...]