Patient/caregiver was educated on contraindications for using Tofranil as follows: Tofranil use, especially along with a few other antidepressants, such as, citalopram, fluoxetine, and sertraline, can significantly increase the serotonin levels in the body and lead to development of serotonin syndrome. Caution must be exercised even when discontinuing on any of the above mentioned antidepressant medications with potential to increase serotonin levels and starting on Tofranil, by observing a window period of atleast 2 weeks, [...]

Patient/caregiver was educated on contraindications for using Tofranil as follows: Tofranil can interact with a number of other medications and can precipitate serious reactions. If you are being newly started on Tofranil, discuss with your physician regarding all other medications you are currently taking and their safety with Tofranil. Also, if you have been taking Tofranil for long, discuss with your physician regarding your history of Tofranil intake, when you are being started on any [...]

Patient/caregiver was educated on the side effects of using Tofranil as follows: Musculoskeletal side effects Tofranil intake carries the risk of lowering the threshold for seizures, thereby, resulting in seizure activity, especially in individuals with history of the same. Tofranil intake can also induce a life-threatening reaction called Neuroleptic malignant syndrome. Individuals taking Tofranil can present with high fever, episodes of confusion, muscle rigidity, elevated blood pressure, and rapid heart rate. Severe cases can present [...]

Patient/caregiver was educated on the side effects of using Tofranil as follows: Central nervous system side effects Tofranil can induce some dizziness and make one drowsy. Starting the medication at a low dose, watching for the response, and gradually changing the dose, to help optimum control of your symptoms, can contribute to controlling/reducing the risk for drowsiness and dizziness due to the medication. If the dizziness becomes bothersome, report it to your physician and other [...]

Patient/caregiver was educated on the side effects of using Tofranil as follows: Serotonin syndrome Tofranil use, especially along with a few other antidepressants, such as, citalopram, fluoxetine, and sertraline, can significantly increase the serotonin levels in the body and lead to development of serotonin syndrome. Individuals can present with mania, excitement, hallucinations, agitation, insomnia, pounding heartbeat, very rapid heart rate, overactive reflexes, and diarrhea. Vision changes Tofranil can result in pupillary dilation and obstruction to [...]