Therapeutic Uses and Mechanism of Action of Metoclopramide

Patient/caregiver was instructed upon therapeutic uses and mechanism of action of Metoclopramide as follows: Metoclopramide is a medication mainly used to enhance motility of bowels in individuals with history of hypomotility. Metoclopramide is also used to reduce nausea and vomiting and counter GERD.  Metoclopramide has multiple mechanisms of action, in order to accomplish these actions, as discussed below. Nausea and vomiting Vomiting center in the brain has dopamine receptors. Stimulation of these dopamine receptors in [...]

Therapeutic Uses and Mechanism of Action of Megestrol

Patient/caregiver was instructed upon therapeutic uses and mechanism of action of Megestrol as follows: Megestrol is a synthetic progesterone sex hormone. Megestrol can be used as an antineoplastic medication, which brings about hormonal changes contributing to inhibitory effects on the growth of tumor masses in the breast and uterine tissues. Excessive exposure to estrogen in women is considered to be an important factor stimulating the growth of established tumors along with development of new tumors [...]

Factors Influencing Melatonin Production-2

Patient/caregiver was instructed upon factors influencing production of melatonin as follows: Night shifts Individuals working night shifts can experience disruption of their natural melatonin cycles, owing to their shift work, which can result in disruption of their sleep-wake cycle. Blindness Exposure to sunlight during the day not only inhibits the production of melatonin during the day, but also sets the ground from normal production of melatonin during the night. Blind individuals, due to their poor [...]

Factors Influencing Melatonin Production-1

Patient/caregiver was instructed upon factors influencing production of melatonin as follows: Exposure to sunlight Natural sunlight during the day inhibits the production of melatonin during the day and sets the ground from normal production of melatonin during the night, thus helping to promote the regular sleep-wake cycle. Darkness Exposure to darkness during the night promotes the production of melatonin in the night, thus helping to induce the sleep. Travel across time zones Individuals traveling across [...]