Patient/caregiver was educated on precautions to be exercised while taking Colchicine as follows: The metabolites of Colchicine along with the significant unmetabolized portion of the administered drug are excreted primarily in the urine and partially in feces. Individuals with compromised renal function cannot perform the drug clearance from the body normally, which allows the drug to stay in blood circulation for longer time, resulting in toxicity and consequent side-effects. So, Colchicine must be used with [...]

Patient/caregiver was educated on precautions to be exercised while taking Colchicine as follows: Colchicine intake can sometimes result in severe muscle pain from muscle breakdown, with release of muscle protein into the blood. Due to their bigger size, these muscle proteins could get trapped in the kidneys, thus blocking the renal circulation and resulting in severe renal failure and compromised urine formation. Individuals with history of compromised renal function should be extra careful with this [...]

Patient/caregiver was educated on precautions to be exercised while taking Colchicine as follows: Observe compliance with recommendation on other pain medication intake, if you are prescribed medications such as, ibuprofen and naproxen, for better control of acute pain and inflammation. Compliance with pain medication intake can complement overall therapeutic benefit of Colchicine intake. Avoid drinking alcohol, especially beer, with Colchicine. Beer has high purine content, which increases risk for high amounts of uric acid production [...]

Patient/caregiver was educated on precautions to be exercised while taking Colchicine as follows: Many other medications, such as, antibacterial and antifungal antibiotics, cholesterol lowering drugs, can influence the metabolism of Colchicine in the body. Avoid drinking grapefruit juice along with Colchicine, as it can also influence the metabolism of Colchicine in the body. Slowdown of Colchicine metabolism can contribute towards accumulation of the drug in the body, thus leading to development of toxic side-effects. If [...]

Patient/caregiver was educated on precautions to be exercised while taking Colchicine as follows: Colchicine intake can result in diarrhea and abdominal pain. The abdominal pain and diarrhea can be self-limiting and resolve in due course of time. Proper hydration measures and compliance with daily fluid intake and rehydration measures recommended can help with relief from fluid and electrolyte loss due to diarrhea. If you experience any further bothersome diarrhea, report it to your physician for [...]