Patient/caregiver was instructed upon therapeutic uses of dothiepin as follows: Major depression: Dothiepin increases the serotonin and noradrenaline concentrations and enhances their actions at the junction between nerve cells. This helps with contributing to increased alertness, enhanced memory & attention, and promotion of feelings of well-being, contentment, and happiness. This leads to relief from anxiety and control of depression symptoms. Panic disorders, phobias, and anxiety: By improving the concentrations and promoting the actions of serotonin and noradrenaline [...]

Patient/caregiver was instructed upon dothiepin and mechanism of action as follows: Neurotransmitters are chemical messengers that are synthesized in the brain and spinal cord. These chemicals are released at nerve endings, into the junction between two nerve cells and help the nerve cells to communicate with each other. These chemicals can have multiple roles and functions in the body. Serotonin is one such chemical considered to reduce anxiety and promote happiness and well-being. Noradrenaline is [...]