Therapeutic Uses and Mechanism of Action of Carbidopa-Levodopa

Patient/caregiver was instructed upon therapeutic uses and mechanism of action of Carbidopa-Levodopa as follows: Carbidopa-Levodopa is a medication that is a combination of two drugs, levodopa and carbidopa. This combination therapy of levodopa and carbidopa is used in the treatment of symptoms of parkinson’s disease, which is caused by low levels of the neurotransmitter, dopamine, in the brain and nervous tissues. Blood-brain barrier is a highly selective membrane barrier, rich in lipid, around the brain, [...]

Pathophysiology of Parkinson’s Disease

Patient/caregiver was educated on pathophysiology of Parkinson’s disease as follows: Parkinson’s disease is caused by low levels of a neurotransmitter, dopamine, in the brain. Dopamine is synthesized and secreted by certain nerve cells in the brain. Dopamine helps with transmission of nerve impulse between the brain cells and regulate smooth initiation and execution of movements. Secondary to use of various drugs or infections or chemicals, these dopaminergic neurons in the brain could be damaged. This [...]