Patient/caregiver was educated on the contraindications of using Zyprexa as follows:
- Zyprexa can interact with many antibacterial and antifungal antibiotics, antiarrhythmic medications, antidepressants, and other antipsychotic medications, resulting in development or aggravation of underlying cardiac arrhythmias, leading to debility and sudden cardiac death. Avoid taking Zyprexa along with medications belonging to the above-mentioned groups, to prevent any dangerous arrhythmias from developing.
- Zyprexa must be cautiously used in individuals with history of seizure disorder, as Zyprexa intake carries the risk of lowering the threshold for seizures, thereby, resulting in seizure activity.
- Zyprexa is extensively metabolized in the liver. If liver function is deficient, the metabolism of Zyprexa can be compromised. This can lead to increased blood levels of the medication for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. So, Zyprexa could be avoided in individuals with hepatic dysfunction and an alternative medication considered or used with caution, with periodical monitoring for liver functions and development of any toxic symptoms.
