Patient/caregiver was educated on side effects of using Zoloft as follows:

Musculoskeletal side-effects

  1. Zoloft intake carries the risk of causing seizures, especially in individuals with history of seizures. Individuals can present with sudden episodes of loss of consciousness, intense convulsions with muscle contractions, bowel and bladder incontinence. Do not ignore seizure episodes and report them to your physician promptly for any appropriate measures to be considered.
  2. Zoloft intake can also induce a life-threatening reaction called Neuroleptic Malignant Syndrome (NMS). Individuals with NMS can present with high fever, episodes of confusion, intense muscle rigidity and contractions, elevated blood pressure, and rapid heart rate.
  3. Potassium ion usually is maintained within close limits in the blood and body fluids and any sudden increase or decrease in blood potassium levels can lead to severe cardiac arrhythmias. Uncontrolled seizure activity and intense muscle contractions from zoloft use can lead to muscle damage and breakdown. Potassium ion from within the damaged muscle cells can leak out into the blood and body fluids, thus causing an acute increase in blood potassium levels. This acute elevation of potassium levels in the blood from zoloft use can lead to life-threatening cardiac arrhythmias. Individuals can present with episodes of chest pain, intense shortness of breath, altered heartbeat, ineffective heart contractions, dizziness/loss of consciousness from arrhythmias. Report them to your physician promptly for any appropriate measures to be considered.

Genitourinary side-effects                                                                               

  1. Zoloft can also induce frequency of urination or polyuria. Individuals with history of poorly controlled diabetes, frequent urinary tract infections, and intake of diuretics can also present with frequent urination. Such individuals taking zoloft, must be aware of this side-effect, as zoloft can aggravate the discomfort of polyuria significantly. Severely increased frequency of urination can contribute to loss of body fluid and dehydration. Dehydrated individuals can present with low blood pressure, episodes of confusion, increased risk for falls & accidents, and increased risk for urinary tract infections. Observing compliance with timed voiding recommendations and other hygienic practices can help reduce the discomfort of polyuria. Compliance with daily fluid intake recommendations and rehydration measures can help with preventing dehydration and development of any UTIs.