Patient/caregiver was educated on contraindications for using Vilazodone as follows:
- Vilazodone use in expectant mothers could harm the unborn baby and result in birth defects. So, vilazodone should be cautiously used or avoided for an alternative drug during pregnancy and in women planning for pregnancy. Women in the child-bearing age group, taking vilazodone on a regular basis, must employ effective contraceptive measures in order to avoid getting pregnant.
- Vilazodone is extensively metabolized in the liver and metabolites are excreted in the urine and feces. If liver function is deficient, the metabolism of Vilazodone can be compromised. In this case, vilazodone can stay in the body for prolonged duration of time in comparison to normal leading to increased blood levels of the medication for longer periods of time. This can lead to increased risk for side-effects and consequent toxicity. So, Vilazodone could be cautiously administered or avoided for an alternative medication, in individuals with hepatic dysfunction. Periodical labs for liver function could be ordered and individuals monitored for development of any toxic symptoms. Discuss with your physician regarding history of compromised liver function, if any.
- Vilazodone intake carries the risk of causing seizures, especially in individuals with history of seizures. Individuals can present with sudden episodes of loss of consciousness, intense convulsions with muscle contractions, bowel and bladder incontinence. Vilazodone is contraindicated or cautiously administered in individuals with history of seizures.
