Patient/caregiver was educated on precautions to be exercised while taking Tofranil as follows:
- Tofranil can also induce retention of urine in the bladder and difficulty with emptying the bladder and so, must be avoided/administered with caution in individuals with history of difficulty passing urine. Individuals with history of retention of urine and frequent urinary tract infections must be aware of this side-effect, as Tofranil can exacerbate this condition significantly. Observing compliance with proper hydration measures, compliance with daily fluid intake recommendations, timed voiding, hygienic practices, and other UTI prevention measures can help reduce the risk of urinary retention and prevent development of any UTIs, secondary to Tofranil intake.
- Tofranil use can sometimes increase the risk for deterioration and worsening of clinical symptoms of mood disorders. Continue taking Tofranil, as recommended, even if your mood feels better and discontinuing the medication abruptly, without your physician’s recommendation, can result in disruption of chemical balance in the brain, resulting in worsening of mood disorder and severe withdrawal symptoms. Individuals can present with complaints such as, feeling low, anxiety, panic attacks, trouble sleeping, gross appetite changes, impulsiveness, agitation, aggression, hallucinations, mania, and suicidal thoughts. Report any deterioration of symptoms of mood disorder immediately to your physician, so that, a dose change or change in plan of care could be considered.
