Patient/caregiver was educated on precautions to be exercised while taking Tofranil as follows:

  1. Notify your doctor of any unresolved and worsening anxiety and depressive symptoms or continuing unpleasant side-effects, so that, your dosage on the medication could be revised.
  2. As the balance between the chemicals in the brain has to be finely regulated to help relieve the anxiety and depressive symptoms and experience feelings of well-being, the dose of Tofranil also needs to be finely regulated, in order to accomplish this goal. Your physician could change the dose of Tofranil, based on the response and side-effects developed. Maintain compliance with follow-up physician appointments and be accommodative to the plan of dose changes, until you show an optimum response.
  3. If you miss a dose, try taking it at the earliest notice of noncompliance. If it is time for the next dose, skip the missed dose and take the dose scheduled. Do not take an extra dose to try making up for the missed dose. Notify your doctor and other health care personnel regarding your dose noncompliance.
  4. Observe compliance with all physician visits and periodical lab draws ordered, while taking Tofranil, for an update on improvement/deterioration with symptoms of mood disorder and side-effects developed. This will also allow your physician to make appropriate changes in your plan of care, as needed.