Patient/caregiver was educated on the side effects of using Tofranil as follows:

Gastrointestinal side-effects                                                                                                            

• Tofranil use can result in common general constitutional symptoms such as, nausea and vomiting. Taking dose of Tofranil with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication.
• Tofranil can also induce extreme dry mouth and constipation. Sucking on a sugar free hard candy can help with symptomatic relief of dry mouth. Proper hydration measures and compliance with daily fluid intake recommendations can help with relief from constipation. If you experience any further bothersome constipation, report it to your physician for a recommendation on laxative/stool softener use. Observing compliance with fiber intake recommendations in the diet can also help with preventing episodes of constipation with the medication.

Cardiovascular side effects

• Tofranil carries the risk of lowering the blood pressure. Hypotension, secondary to Tofranil intake, can lead to episodes of confusion and dizziness, thus increasing the risk for fall and accidents.
• Tofranil also carries the risk of causing and/or aggravating cardiac arrhythmias, leading to severe debility and death. Individuals can present with episodes of chest pain, rapid heart rate, palpitations, dizziness, and shortness of breath.