Patient/caregiver was instructed upon therapeutic uses of Tofranil as follows:
Major depression
- Tofranil, by inhibiting the reuptake of serotonin and noradrenaline, enhances the actions of these chemicals in the nerve cells.
- This helps with improved communication, appropriate desired nerve stimulation, thus contributing to controlling symptoms of depression, such as, disturbed sleep, diminishing appetite, compromised energy levels, exhaustion, and lack of interest in activities of daily living.
Bed-wetting in children
- Action of the neurochemical acetylcholine on the smooth muscle of bladder results in contraction of bladder, bladder emptying, and urination.
- Tofranil reportedly inhibits the action of acetylcholine on the bladder and thus, inhibits bladder emptying. This action of Tofranil helps with preventing/reducing episodes of nocturnal urination and bed-wetting in children.
