Patient/caregiver was educated on the side-effects of using Pregabalin as follows:
Genitourinary side-effects
- Pregabalin, on prolonged use, carries the risk of muscle damage, muscle breakdown, and consequent muscle pain. Muscle proteins, released from breakdown of muscle, circulate in the blood stream and enter the kidneys to be eliminated in the urine. These proteins are considerably big in size, cannot be filtered in the urine, and so, get clogged up in the glomeruli (filtering units) of kidneys. This can progressively reduce the filtering ability of kidneys and contribute to diminishing renal function, compromised excretion of waste metabolites, and reduced urine volume.
- Reduced urine volume can lead to reduced excretion in urine and increased accumulation of fluid and waste metabolites in the body, generalized body edema and swelling, increased shortness of breath, and weight gain. Reduced excretion of waste metabolites in the urine can contribute to altered levels of consciousness, sleep disturbances, and skin rash & persistent itching.
