Patient/caregiver was educated on contraindications for using Nitrofurantoin as follows:
- Prolonged use of Nitrofurantoin can result in deficiency of enzyme systems needed to maintain the integrity of red blood cells. This can result in poor red blood cell integrity, predisposing the cells to lysis, contributing to development of hemolytic anemia. This breakdown of red blood cells, secondary to Nitrofurantoin intake, can result in elevated levels of the yellow pigment, bilirubin, in the blood. This can result in signs and symptoms of jaundice, such as, itching, dark urine, yellowing of skin and eyes, nausea and vomiting, poor metabolism, and fatigue. Secondary to breakdown of red blood cells and consequent anemia, individuals can also present with pallor of skin, episodes of confusion, dizziness, exacerbated shortness of breath, and compromised endurance. Nitrofurantoin is contraindicated in individuals with history of hemolytic anemia or used with extreme caution, with close watch maintained for development of symptoms of jaundice and anemia.
- Do not take Nitrofurantoin, if you ever manifested any allergic response to intake of Nitrofurantoin. Discuss your history of allergic response to this medication with your physician, without fail.
