Patient/caregiver was educated on contraindications for using Mitigare as follows:
- In the event of any current manifestations of any allergic response with this medication, report it to your physician or other health care personnel immediately, to check regarding your safety with continuing on intake of this medication.
- The metabolites of Mitigare along with the significant unmetabolized portion of the administered drug are excreted primarily in the urine and partially in feces. Individuals with compromised renal function cannot perform the drug clearance from the body normally, which allows the drug to stay in blood circulation for longer time, resulting in toxicity and consequent side-effects. So, Mitigare must be used with caution in individuals with compromised renal function, with possible multiple dose adjustments, periodical monitoring for renal functions, and close watch for development of any dangerous side-effects and toxicity symptoms with the medication.
