Patient/caregiver was educated on contraindications for using Megace as follows:
- Megace intake can result in elevated blood sugars. Diabetic individuals, especially with history of poorly controlled blood sugars can be at increased risk for episodes of severe hyperglycemia, secondary to Megace intake. Individuals can present with symptoms of hyperglycemia such as, episodes of confusion, dry mouth, frequent urination, increased thirst and hunger, dry skin, and blurred vision. Megace could be avoided or used with extreme caution in diabetic individuals with history of poor blood sugar control.
- Megace is mainly excreted by the kidneys. Individuals with renal disease cannot excrete Megace metabolites normally. The medication metabolites can stay in blood circulation for longer time, resulting in increased risk for side-effects and consequent toxicity. So, Megace could be avoided in individuals with renal dysfunction and an alternative medication considered or used with caution, with periodical monitoring for renal function and development of any toxic symptoms.
