Patient/caregiver was educated on precautions to be exercised while taking Digitek as follows:
- Absorption of Digitek could be inhibited by foods rich in fiber, such as brown rice, green leafy vegetables, and bran. Absorption of Digitek could also be inhibited by antacids, such as, milk of magnesia and drugs used to reduce cholesterol, such as, cholestyramine and colestipol, thus compromising the therapeutic benefits of Digitek intake. So, try to space out Digitek by atleast 2 – 3 hours with any food items rich in fiber content, antacid medications, and drugs used to reduce cholesterol.
- Digitek is minimally metabolized in the liver to active metabolites, which along with the significant unmetabolized portion of the drug is eliminated by kidneys in the urine. If renal function is deficient, the elimination of these compounds could be compromised. This can lead to increased blood levels of the medication and metabolites for longer periods of time, resulting in increased risk for side-effects and consequent toxicity with Digitek. So, in individuals with history of compromised renal function, Digitek must be used with extreme caution, closely monitored dose adjustments, periodical monitoring for renal functions and development of any toxicity symptoms with the medication. Observe close compliance with any labs ordered for renal function evaluation, while taking Digitek.
