Patient/caregiver was educated on contraindications for using Digitek as follows:
- Digitek is minimally metabolized in the liver to active metabolites, which along with the significant unmetabolized portion of the drug is eliminated by kidneys in the urine. If renal function is deficient, the elimination of these compounds could be compromised. This can lead to increased blood levels of the medication and metabolites for longer periods of time, resulting in increased risk for side-effects and consequent toxicity with Digitek. So, in individuals with history of compromised renal function, Digitek must be used with extreme caution, closely monitored dose adjustments, periodical monitoring for renal functions and development of any toxicity symptoms with the medication.
- In the event of any current manifestations of any allergic response with this medication, report it to your physician or other health care personnel immediately, to check regarding your safety with continuing on intake of this medication.