Patient/caregiver was educated on Rosiglitazone and its mechanism of action as follows:

  1. Rosiglitazone is an oral antidiabetic drug, used in patients with type-2 diabetes.
  2. Insulin is a hormone produced by the pancreas in your body. Insulin helps with shifting the glucose in the blood into the cells of body tissues. This helps with regulating the blood sugar levels and providing nutrition to the cells of body tissues.
  3. Type-2 diabetes is a condition in which your body becomes resistant to the action of insulin. Resistance to action of insulin hormone leads to poor shifting of glucose in the blood into the cells of body tissues. This leads to poor regulation of blood sugar levels with higher blood sugar numbers and poor nutrition supply to the cells of body tissues. Reduced nutrition supply to body tissues can contribute to diabetes symptoms, such as, feeling very tired, confusion, and blurred vision.

Rosiglitazone helps with regulating the blood sugar control and management of Type-2 diabetes by the following mechanisms:

  1. Rosiglitazone is mostly used in individuals resistant to the action of insulin.
  2. Rosiglitazone acts by reducing insulin resistance and increasing the sensitivity of body cells to insulin. Rosiglitazone also results in synthesis of new fat cells.
  3. Improved/reduced insulin resistance by Rosiglitazone can contribute to increased response to insulin with improved shifting of glucose from the blood into the cells of body tissues.
  4. Increased glucose shifting into the cells leads to lowered blood sugar numbers and improved regulation of blood sugars. Increased glucose shifting into the cells contribute to better nutrition supply to the cells of body tissues. Improved nutrition supply to body tissues result in improvement in diabetes symptoms, such as, feeling very tired and confusion.
  5. Control of blood sugars over time with rosiglitazone also results in lowering of hemoglobin A1c, which is a lab indicator of chronic blood glucose control, over the past 3 months.
  6. Rosiglitazone can be used either alone or in combination with other antidiabetic medications for improved control of blood sugars.