Patient/caregiver was educated on contraindications for using Prozac as follows:
- Prozac carries significant risk for obstruction to the flow of aqueous humor, increasing the intraocular pressure, eye pain, headache, blurred vision with haloes around light, and compromised vision. So, Prozac use is contraindicated in individuals with history of glaucoma, especially the closed-angle glaucoma.
- Prozac can interact with many antibacterial and antifungal antibiotics, antiarrhythmic medications, antidepressants, and antipsychotic medications, resulting in development or aggravation of underlying cardiac arrhythmias, leading to debility and sudden cardiac death. Avoid taking Prozac along with medications belonging to the above-mentioned groups, to prevent any dangerous arrhythmias from developing.
- Prozac is mainly metabolized in the liver. If liver function is deficient, the metabolism of Prozac can be compromised. This can lead to increased blood levels of the medication and metabolites for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. So, Prozac could be avoided in individuals with hepatic dysfunction and an alternative medication considered or used with caution, with periodical monitoring for liver functions and development of any toxic symptoms.
