Patient/caregiver was educated on the precautions to be observed while taking prednisone as follows:
- Prednisone intake can result in sodium and water retention with loss of potassium from the body. Increased sodium and fluid volume in circulation can contribute to elevated blood pressure readings. This can predispose hypertensive patients to poor blood pressure control and hypertensive crisis and may necessitate change in dose of antihypertensive medications. Also, low potassium levels, secondary to prednisone intake, can result in serious complications of cardiac arrhythmias. Also, fluid retention with prednisone can add extra load on failing heart and complicate the outcome for individuals with history of CHF. Prednisone should be carefully administered in individuals with history of hypertension, cardiac failure, and arrhythmias, with close monitoring of daily blood pressure readings, symptoms of heart failure, and symptoms of exacerbation of arrhythmia. Every day weight recording is advised in individuals with history of CHF, especially in the wake of prednisone causing fluid retention. Report to your physician regarding any consistently elevated blood pressure readings, worsening edema, exacerbation of episodes of dizziness and confusion, and deteriorating shortness of breath.
- Avoid drinking alcohol with prednisone. Prednisone, by inhibiting synthesis of prostaglandins in the stomach, can predispose an individual to development of peptic ulcers. Alcohol can significantly contribute to this effect by damaging the mucosal lining of the stomach, leading to gastritis and ulcer development.
- Prolonged intake of prednisone can result in increased protein breakdown, muscle loss, weakness, and weight loss. Observe compliance with physical therapy, as endurance allows, in order to maintain the motor strength and preventing loss of muscle mass.
