Patient/caregiver was educated on contraindications for using Primidone as follows:
- Primidone can interact with a lot of other medications, thus resulting in serious side-effects and toxicity. Concomitant administration of alcohol and drugs like OTC cough medications and antihistamines, other opioid medications like hydrocodone and codeine, other muscle relaxant medications, antidepressant medications, antipsychotics, and antianxiety medications, can also result in extreme depression of brain and respirations, thus potentiating the dizziness, confusion, and breathing difficulties caused by primidone and so, must be avoided taking along with primidone.
- Primidone could be avoided for a safer alternative in individuals with history of severe head injury and brain damage. Individuals with history of head injury and brain damage, and severe respiratory disorders can be at a very high risk to present with severe depression of brain and associated respiratory and cardiovascular centers with primidone, respiratory center with primidone, leading to complications such as, coma, respiratory arrest, dangerous hypotension, and bradycardia, which can be fatal.
