Patient/caregiver was educated on the side-effects of using Primidone as follows:

Gastrointestinal side-effects                                                                                                            

  1. Primidone use can result in common general constitutional symptoms such as, nausea and vomiting.  Taking dose of primidone with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication.

Metabolic side-effects

  1. Primidone use can result in the induction of some enzymes, which leads to increased metabolism of various other drugs, such as, anticoagulants, antidepressants, many cardiovascular medications, and contraceptive pills. Increased metabolism of these drugs by enzymes will quickly reduce the blood levels of these medications, can compromise their therapeutic benefit, thus necessitating a dose change and/or alternative measures.