Contraindications for Using Actoplus Met-1

Patient was educated on contraindications for using Actoplus Met as follows: Actoplus Met is mainly metabolized in the liver and excreted by the kidneys. Part of it is even excreted unchanged in the urine. If liver and kidney function are deficient, the metabolism and excretion of this medication can suffer. This can lead to increased blood levels of the medication for longer periods of time, resulting in toxicity and severe side effects. So, Actoplus Met [...]

Therapeutic Uses and Mechanism of Action of Metoclopramide

Patient/caregiver was instructed upon therapeutic uses and mechanism of action of Metoclopramide as follows: Metoclopramide is a medication mainly used to enhance motility of bowels in individuals with history of hypomotility. Metoclopramide is also used to reduce nausea and vomiting and counter GERD.  Metoclopramide has multiple mechanisms of action, in order to accomplish these actions, as discussed below. Nausea and vomiting Vomiting center in the brain has dopamine receptors. Stimulation of these dopamine receptors in [...]

Therapeutic Uses of Tamoxifen-2

Patient/caregiver was instructed upon therapeutic uses of tamoxifen as follows: Breast cancer Increased binding of estrogen to the estrogen receptors and the consequent response of proliferation of the breast tissue, is considered to play a significant role in the growth of tumors in the breast tissue. Tamoxifen has an antiestrogenic effect on the breast tissue. Binding of tamoxifen to the estrogen receptors in the breast tissue progressively modulate these receptors and reduces response of these [...]

Therapeutic Uses of Tamoxifen-1

Patient/caregiver was instructed upon therapeutic uses of tamoxifen as follows: Tamoxifen is a medication that belongs to a class of drugs that selectively bind to estrogen receptors located in different body tissues and modulate or alter their function. After binding to the estrogen receptors, depending on the target tissue involved, tamoxifen can have both estrogenic and antiestrogenic effects. Anovulation in women Appropriate release of sex hormones from the hypothalamus and pituitary glands is needed for [...]

Tamoxifen and Mechanism of Action

Patient/caregiver was instructed upon tamoxifen and mechanism of action as follows: Tamoxifen is a medication that belongs to a class of drugs that selectively bind to estrogen receptors located in different body tissues and modulate or alter their function. This group of drugs are called selective estrogen receptor modulators (SERMs). Tamoxifen is mainly used in the treatment of estrogen responsive breast cancer in men and women, apart from other treatment modalities, such as, surgery, radiation, [...]