Pathophysiology of Seizures

Patient/caregiver was instructed upon the pathophysiology of seizures as follows: Nerve impulses in the brain are transmitted from one cell to the other as mild electrical impulses. Many factors such as, neurotransmitters in the brain, sodium and glucose concentrations in the blood, bacterial infections, blood and oxygen supply to the brain, and mechanical injury to the brain play a significant role in influencing these nerve impulses in the brain. Some of these factors can act [...]

Precautions to be Exercised While Taking Primidone-7

Patient/caregiver was educated on precautions to be exercised while taking primidone as follows: The active metabolites of primidone have significant pharmacological actions as the parent compound primidone. These metabolites along with the unmetabolized portion of primidone are mainly excreted in the urine.  Individuals with renal disease cannot excrete them normally, which allows them to stay in blood circulation for longer time, resulting in toxicity and consequent side-effects. So, primidone could be avoided in individuals with [...]

Precautions to be Exercised While Taking Primidone-6

Patient/caregiver was educated on precautions to be exercised while taking primidone as follows: Primidone only prevents the seizures from happening by reducing the excitation and rapid firing of the nerves. But, primidone does not fix the actual condition causing the seizures. Continue taking primidone as ordered, even if you experience relief from the symptoms. Abrupt discontinuation on primidone intake can result in recurrence of seizure episodes and life-threatening status epilepticus. Discontinuing the medication should only [...]

Precautions to be Exercised While Taking Primidone-5

Patient/caregiver was educated on precautions to be exercised while taking primidone as follows: Primidone use carries the risk of inducing/aggravating motor incoordination, resulting in clumsiness and unsteadiness during coordinated activities, such as, walking. Primidone use can also result in abnormal uncontrolled eye movements, such as, rolling of the eyes, contributing to double vision. The confusion and poor motor coordination, secondary to primidone intake, with the added effect of double vision primidone can cause, significantly increases [...]

Precautions to be Exercised While Taking Primidone-4

Patient/caregiver was educated on precautions to be exercised while taking primidone as follows: Primidone carries a potential for addiction and abuse. Individuals with history of substance abuse have an increased chance for addiction with primidone use. Notify your doctor regarding your history of substance abuse, so that, your plan of care could be revised and an alternative medication could be prescribed for control of seizure activity. Patients with history of mood disorders, secondary to primidone [...]