Contraindications for Nitrofurantoin Use-4

Patient/caregiver was educated on contraindications for using Nitrofurantoin as follows: The unmetabolized portion of Nitrofurantoin along with the metabolites is excreted in the urine. Individuals with renal disease cannot excrete these active metabolites normally, which allows them to stay in blood circulation for longer time, resulting in toxicity and consequent side-effects. Individuals in toxicity with Nitrofurantoin can present with anemia, shortness of breath, cough, chest pain, neuropathy with tingling and numbness in the extremities, dark [...]

Contraindications for Nitrofurantoin Use-3

Patient/caregiver was educated on contraindications for using Nitrofurantoin as follows: Nitrofurantoin, especially with prolonged use, carries the risk for compromised lung function, leading to episodes of exacerbation of shortness of breath, cough, and chest pain. So, Nitrofurantoin could be avoided for a safer antibiotic or used with extreme caution, in individuals with history of compromised lung function and chronic lung disease. Nitrofurantoin needs acid medium in the stomach for better absorption. When used concurrently, antacids [...]

Contraindications for Nitrofurantoin Use-2

Patient/caregiver was educated on contraindications for using Nitrofurantoin as follows: Nitrofurantoin is significantly metabolized in the liver and if liver function is deficient, the metabolism of Nitrofurantoin can be compromised. This can lead to increased blood levels of the medication for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. Also, long term Nitrofurantoin intake also can lead to hepatic injury, thus compromising liver function. Hepatic injury and altered liver function [...]

Contraindications for Nitrofurantoin Use-1

Patient/caregiver was educated on contraindications for using Nitrofurantoin as follows: Prolonged use of Nitrofurantoin can result in deficiency of enzyme systems needed to maintain the integrity of red blood cells. This can result in poor red blood cell integrity, predisposing the cells to lysis, contributing to development of hemolytic anemia. This breakdown of red blood cells, secondary to Nitrofurantoin intake, can result in elevated levels of the yellow pigment, bilirubin, in the blood. This can [...]

Side Effects of Nitrofurantoin-4

Patient/caregiver was educated on the side-effects of using Nitrofurantoin as follows: Hematologic side-effects                                                                              Prolonged use of Nitrofurantoin can result in deficiency of enzyme systems needed to maintain the integrity of red blood cells. This can result in poor red blood cell integrity, predisposing the cells to lysis, contributing to development of hemolytic anemia. Long term Nitrofurantoin intake also can lead to hepatic injury, thus compromising liver function. This breakdown of red blood cells, hepatic injury, [...]