Contraindications for Taking Pioglitazone

Patient was educated on contraindications for taking Pioglitazone as follows: Pioglitazone is mainly metabolized in the liver. If liver function is deficient, the metabolism of this medication can suffer. This can lead to increased blood levels of the medication for longer periods of time, resulting in toxicity and severe side effects. So, Pioglitazone should be used with caution in individuals with hepatic dysfunction. Pioglitazone is also known to cause deterioration in liver function and consequently, [...]

Side Effects of Pioglitazone Use-2

Patient was educated on the side effects of using Pioglitazone as follows: Hypoglycemia Pioglitazone by decreasing the insulin resistance, can result in excessive uptake of glucose and lead to reduced blood sugars. But, hypoglycemia with Pioglitazone is not a common complaint, unless it is used in combination with other medications, which have a significant risk for side effect of hypoglycemia, such as, Glimepiride and Glyburide. Macular edema Pioglitazone can result in macular edema and consequently, [...]

Side Effects of Pioglitazone Use-1

Patient was educated on the side effects of using Pioglitazone as follows: Fluid retention Pioglitazone can result in significant fluid retention and can cause complications in individuals with congestive heart failure. Patients can present with edema, weight gain, trouble breathing, shortness of breath, and fatigue. Osteoporosis Pioglitazone can also result in weakening of the skeletal framework, resulting in osteoporosis and pathological fractures. Muscle pain Pioglitazone can significantly increase risk of muscle and skeletal pains and [...]

How to Take Pioglitazone

Patient was educated on how to take Pioglitazone as follows: Take Pioglitazone at the same time every day, to avoid forgetting the medication. Maintain good regular eating habits. Do not skip your meals. Maintain compliance with your dietary recommendations, as ordered. Maintain compliance with any exercise scheduled prescribed by your doctor. Try not to overdo on your exercise. Take weight reading at least twice a week and maintain a log of every reading for comparative [...]

Pioglitazone and Mechanism of Action

Patient was educated on Pioglitazone and its mechanism of action as follows: Pioglitazone is an oral antidiabetic medication, used especially in patients with type-2 diabetes. Individuals with type 2 diabetes develop resistance to insulin produced in the body. So, they present with elevated blood sugar. Pioglitazone acts by reducing insulin resistance and increasing the sensitivity of body cells to insulin. Pioglitazone also results in synthesis of new fat cells. This leads to increased glucose uptake [...]