Patient was educated on the characteristics of diabetic nephropathy as follows:
- Elevated arterial blood pressure – Poorly managed diabetes with prolonged elevated blood glucose lead to chronic inflammation of the blood vessels. Fat deposits in the inflamed blood vessels, narrowing the vessels and thereby, leading to atherosclerosis and elevated blood pressure.
- Prolonged elevated blood pressure in the renal blood vessels lead to deposition of fibrin and changes in the mesangial connective tissue, which contribute to narrowing of glomeruli and poor filtration.
- Changes in the connective tissue of glomeruli lead to increased filtration of bigger molecules, such as albumin, leading to protein loss in urine.
- Progressive narrowing of the glomeruli leads to further diminishing of blood flow and further reduction in the glomerular filtration rate and gradually, patient ends up with end stage renal disease, where one must be dependent on dialysis to clear the impurities from the blood or go for a renal transplant.
