Patient was educated on biological effects secondary to use of Captopril follows:
- Inhibition of angiotensin converting enzyme leads to reduced formation of active angiotensin, which results in inhibition of narrowing of blood vessels and thereby, result in reduced blood pressure.
- Inhibition of blood vessel narrowing will lead to more room inside the blood vessel, which allows better blood flow to end organs, such as, heart and kidney.
- Improving oxygenated blood flow to the end organs can help improving the function of end organs, such as, heart and kidney. So, Captopril is very useful in patients with compromised cardiac and renal functions.
- By reducing aldosterone secretion, Captopril contributes to reduced sodium and water retention in the body, thus leading to reduced blood pressure and work load on the heart.
- Lowering of blood pressure can help prevent strokes in patients at risk for stroke.
- Lowering of blood pressure can also lead to progression of chronic kidney disease in patients with compromised renal function.
- Reduced workload on the heart will contribute towards increased performance and efficiency of heart contraction, especially in patients with heart failure.
