Patient was educated on Beta-2 agonists and their mechanism of action as follows:

  1. Beta-2 receptors are located mainly at two sites-Bronchial smooth muscle in the respiratory tract and Smooth muscle of the blood vessels.
  2. Beta-2 agonists are medications that activate these Beta-2 receptors. They are mainly used with regards to their action on Beta-2 receptors of bronchial smooth muscle.
  3. Phosphorylation (Addition of phosphate) of myosin (contractile protein in the smooth muscle) is needed for the myosin to contract, which leads to smooth muscle contraction.
  4. Activation of Beta-2 receptors inhibits phosphorylation of myosin, which inhibits the contraction and promotes relaxation of the bronchial smooth muscle.
  5. Contraction of the bronchial smooth muscle with narrowing of the airways is the major pathology in individuals with history of asthma and COPD.
  6. So, by promoting relaxation of bronchial smooth muscle with dilation of the airways, Beta-2 agonists help individuals with asthma and COPD, to prevent episodes of acute shortness of breath and dyspnea.