Patient/caregiver was educated on contraindications for using Midazolam as follows:
- Midazolam intake can be habit-forming and carries an abuse potential. The risk for addiction and abuse can be even higher, especially in individuals with history of substance abuse. Midazolam must be used with extreme caution or avoided in such individuals, to prevent any abuse and toxic side-effects with Midazolam use.
- Midazolam use in expectant mothers could harm the unborn baby and result in complications, such as, respiratory depression, breathing difficulties, and low BP numbers in newborn. So, Midazolam use should be avoided during pregnancy and in women planning to get pregnant. The possibility of one being pregnant should be explored before initiating therapy with midazolam for a woman in child-bearing age group. Women in the child-bearing age group, taking Midazolam on a regular basis, must employ effective contraceptive measures in order to avoid getting pregnant.
- When taken together, Midazolam can interact with a number of other medications and can precipitate serious reactions. Some medications, such as, oral contraceptives, some antibiotics, anti-GERD agents like omeprazole, inhibit the enzymes needed for the metabolism of Midazolam. Concurrent administration of these medications with Midazolam can inhibit the metabolism of midazolam. Thus, midazolam stays in the body for prolonged duration of time in comparison to normal and stand the risk of causing toxicity.
