Patient/caregiver was educated on contraindications for using Metaxalone as follows:
- Metaxalone should be administered with extreme caution in individuals with history of respiratory disorders, such as, asthma and COPD. Individuals with history of severe respiratory disorders can be at a very high risk to present with depression of respiratory center with the medication. Low oxygen levels in the body with elevated carbon-di-oxide levels can contribute to altered levels of consciousness, sedation, slow & shallow breathing, severely compromised endurance and exercise tolerance, extreme fatigue, and development of seizures.
- Metaxalone, by causing a depressant effect on the brain, can also depress the cardiovascular center in the brain, which regulates the heart rate and blood pressure. Consequently, intake of metaxalone can result in low heart rate and blood pressure. This effect of metaxalone can be profound in individuals with history of hypotension and bradycardia and so, must be administered with extreme caution.
- Do not take Metaxalone, if you ever manifested any allergic response to intake of Metaxalone. Discuss your history of allergic response to this medication with your physician, without fail.
