Patient/caregiver was educated on the side-effects of using Ryanodex as follows:

Dermatologic side-effects

  1. Ryanodex use can contribute to intense skin rash, erythema, and abnormal hair growth.
  2. Ryanodex administered into the vein can result in inflammation of the vein with redness and swelling of the site. Individuals could experience intense pain and tenderness at the site of injection.
  3. In severe cases, ryanodex administered as a shot can result in necrosis of body tissue at the site of injection.

Musculoskeletal side-effects

  1. Ryanodex by causing excessive muscle relaxation can contribute to flaccidity and muscle weakness, which can increase risk for falls and accidents.

Hematologic side-effects

  1. Ryanodex use can rarely lead to bone marrow failure, resulting in low blood cell count. Poor red cell count can lead to development of symptoms of anemia, such as, fatigue, weakness, confusion, dizziness, pale skin, increased heart rate, and shortness of breath. Low white blood cell counts from marrow failure can increase individual’s risk for infections. Low platelet counts due to marrow failure can result in increased risk for hemorrhage and bleeding episodes.