Patient/caregiver was educated on the side-effects of using Ryanodex as follows:
General allergic reactions
- Ryanodex use can result in general allergic reactions, such as, skin rashes, hives, and itching.
- Some patients can present with symptoms of severe allergic and anaphylactic response with ryanodex, such as, difficulty breathing, swelling of face, lips, throat, and tongue, with consequent difficulty breathing. Seek emergency medical help for such findings, especially with difficulty breathing, for any appropriate measures to be considered.
Gastrointestinal side-effects
- Ryanodex can also induce extreme constipation and abdominal distention, leading to functional intestinal obstruction and abdominal pain. Proper hydration measures and compliance with daily fluid intake recommendations can help with relief from constipation. If you experience any further bothersome constipation, report it to your physician for a recommendation on laxative/stool softener use. Observing compliance with fiber intake recommendations in the diet can also help with preventing episodes of constipation with the medication.
- Ryanodex intake can contribute to gastrointestinal irritation and episodes of GI bleeding. Individuals can present with black tarry stools due to the blood from GI bleed getting partially digested before passing out into the stool. Individuals presenting with vomiting can show the GI bleed as coffee grounds in the vomit.
- Ryanodex can also induce hepatic dysfunction and liver toxicity, leading to fatal liver failure. Individuals can present with symptoms of liver failure, such as, jaundice with yellowing of skin and eyes, itching of skin, upper right abdominal pain, abdominal distension, nausea and vomiting, confusion and disorientation, fluid retention in the body with swelling, and compromised appetite.
