Patient was educated on contraindications for using Losartan as follows:
- Do not use this medication if you are allergic to losartan.
- Liver disease
- Losartan is mainly metabolized in the liver and excreted in the bile.
- If liver function is deficient, metabolism and excretion of losartan could be slowed down, thus compromising the therapeutic effects of the medication.
- Renal disease
- A significant part of losartan is also eliminated by the kidneys.
- Individuals with renal disease and diminished renal function cannot eliminate losartan normally, which allows the medication to be in the blood stream longer, thus increasing the risk for side-effects and toxicity with the medication.