Patient/caregiver was educated on precautions to be exercised while taking Lorazepam as follows:

  1. Follow closely on the expiration date of the medication. If using a pillbox, check the expiration date on the medication container every time you fill the pillbox. If you are taking this medication for longer periods of time, set reminders on your phone, one 10 days ahead, the next a week ahead, and then every day, before you run out of the medication. This helps with securing the refill in time and making arrangements for pick-up at the pharmacy. Also, you can avoid the unpleasant withdrawal response from sudden discontinuation of medication due to running out on the medication.
  2. Lorazepam use, especially on empty stomach, can result in common general constitutional symptoms such as, nausea and vomiting. Taking dose of Lorazepam with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication.
  3. Lorazepam can also induce extreme dry mouth and constipation. Sucking on a sugar free hard candy can help with symptomatic relief of dry mouth. Proper hydration measures and compliance with daily fluid intake recommendations can help with relief from constipation. If you experience any further bothersome constipation, report it to your physician for a recommendation on laxative/stool softener use. Observing compliance with fiber intake recommendations in the diet can also help with preventing episodes of constipation with the medication.
  4. Do not take Lorazepam along with alcohol, opioid pain medications, such as, hydrocodone and codeine, antipsychotic medications, antidepressant medications, anti-seizure medications, muscle relaxants, antihistamines, OTC cough syrups, and any other medications that carry a risk for depression of the central nervous system and the respiratory center, resulting in episodes of dizziness, confusion, difficulty breathing, and respiratory arrest. The individual influence of these medications on respirations and central nervous system can get added up, thus leading to severe respiratory depression, confusion, coma, and can even be fatal. Lorazepam must be used with extra caution in individuals with history of breathing issues, such as, asthma and COPD, to prevent development of any episodes of severe SOB and respiratory arrest. Lorazepam, especially when taken in high doses, can also lead to depression of respiratory center in the brain and difficulty breathing. Any exacerbation of shortness of breath, following Lorazepam intake, must be reported to the physician, for any change in plan of care to be made.