Patient/caregiver was instructed upon indications for methimazole use as follows:
- Methimazole is usually prescribed in individuals with overactive thyroid gland, producing excessive levels of thyroid hormone.
- Overactive thyroid gland could be due to various reasons, as follows:
- Individuals with history of Graves’ disease produce autoantibodies that overstimulate the thyroid gland. This overstimulation of thyroid gland by these autoantibodies lead to excessive thyroid hormone production.
- Toxic multinodular goiter is a condition caused by an abnormal growth of thyroid cells that form lumps within the thyroid gland. These lumps are called nodules, which produce excessive thyroid hormone.
- Thyroid gland normally produces thyroxine in response to a hormone, thyroid stimulating hormone (TSH), produced in the brain. Some tumors of brain can result in secretion of excessive levels of TSH, resulting in overstimulation of thyroid gland and consequently, can lead to excessive thyroid hormone production.
- In all these above conditions, methimazole can help to inhibit the thyroid gland from producing thyroid hormone in excess and prevent symptoms of hyperthyroidism from developing.