Patient/caregiver was educated on contraindications for using Mysoline as follows:
- Mysoline can interact with a lot of other medications, thus resulting in serious side-effects and toxicity. Concomitant administration of alcohol and drugs like OTC cough medications and antihistamines, other opioid medications like hydrocodone and codeine, other muscle relaxant medications, antidepressant medications, antipsychotics, and antianxiety medications, can also result in extreme depression of brain and respirations, thus potentiating the dizziness, confusion, and breathing difficulties caused by Mysoline and so, must be avoided taking along with Mysoline.
- Mysoline could be avoided for a safer alternative in individuals with history of severe head injury and brain damage. Individuals with history of head injury and brain damage, and severe respiratory disorders can be at a very high risk to present with severe depression of brain and associated respiratory and cardiovascular centers with Mysoline, respiratory center with Mysoline, leading to complications such as, coma, respiratory arrest, dangerous hypotension, and bradycardia, which can be fatal.
